Interazioni & integrazioni
Forza & invecchiamento
Bibliografia
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Wohlgemuth SE, Seo AY, Marzetti E, Lees HA, Leeuwenburgh C. Skeletal muscle autophagy and apoptosis during aging: effects of calorie restriction and life-long exercise. Exp Gerontol 2010; 45: 138-48.
Luo L, Lu AM, Wang Y et al. Chronic resistance training activates autophagy and reduces apoptosis of muscle cells by modulating IGF-1 and its receptors, Akt/mTOR and Akt/FOXO3a signaling in aged rats. Exp Gerontol 2013; 48(4): 427-36.
Marzetti E, Leeuwenburgh C. Skeletal muscle apoptosis, sarcopenia and frailty at old age. Exp Gerontol 2006; 41: 1234-8.
Marzetti E, Wohlgemuth SE, Lees HA, Chunget al. Age-related activation of mitochondrial caspase-independent apoptotic signaling in rat gastrocnemius muscle. Mech Ageing Dev 2008; 129: 542-9.
Bodine SC, Stitt TN, Gonzalez M et al. Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo. Nat Cell Biol 2001; 3: 1014-9.
Glass DJ. Molecular mechanisms modulating muscle mass. Trends Mol Med 2003; 9: 344-50.
Schiaffino S, Mammucari C. Regulation of skeletal muscle growth by the IGF1-Akt/PKB pathway: insights from genetic models. Skelet Muscle 2011; 1: 4.
Oldham S, Hafen E. Insulin/IGF and target of rapamycin signaling: a TOR de force in growth control. Trends Cell Biol 2003; 13: 79-85.
American College of Sports Medicine. Exercise and Physical Activity for Older Adults: position stand. Med Sci Sports Exerc 2009; 41(7): 1510-30.