Bibliografia

1. Lundholm K, Korner U, Gunnebo L, et al. Insulin treatment in cancer cachexia: effects on survival, metabolism, and physical functioning. Clin Cancer Res 2007; 13: 2699-706.
2. Del Fabbro E, Hui D, Dalal S, et al. Clinical outcomes and contributors to weight loss in a cancer cachexia clinic. J Palliat Med 2011; 14: 1004-8.
3. Keller C, Keller P, Giralt M, Hidalgo J, Pedersen BK. Exercise normalises overexpression of TNFalpha in knockout mice. Biochem Biophys Res Commun 2004; 321: 179-82.
4. Pedersen BK, Hoffman-Goetz L. Exercise and the immune system: regulation, integration, and adaptation. Physiol Rev 2000; 80: 1056-73.
5. Petersen AM, Pedersen BK. The anti-inflammatory effect of exercise. J Appl Physiol 2005; 98: 1154-62.
6. Van Zee KJ, Kohno T, Fischer E, et al. Tumor necrosis factor soluble receptors circulate during experimental and clinical inflammation and can protect against excessive tumor necrosis factor alpha in vitro and in vivo. Proc Natl Acad Sci 1992; 89: 4845-9.
7. Steensberg A, Keller C, Starkie RL, et al. IL-6 and TNF-alpha expression in, and release from, contracting human skeletal muscle. Am J Physiol Endocrinol Metab 2002; 283: E1272-8.
8. Pedersen M, Steensberg A, Keller C, et al. Does the aging skeletal muscle maintain its endocrine function?. Exerc Immunol Rev 2004; 10: 42-55.
9. Moldoveanu AI, Shephard RJ, Shek PN. Exercise elevates plasma levels but not gene expression of IL-1β, IL-6, and TNF-α in blood mononuclear cells. J Appl Physiol 2000; 89: 1499-504.
10. Nehlsen-Cannarella SL, Fagoaga OR, Nieman DC, et al. Carbohydrate and the cytokine response to 2.5 h of running. J Appl Physiol 1997; 82: 1662-7.
11. Nara M, Kanda T, Tsukui S, et al. Running exercise increases tumor necrosis factor-α secreting from mesenteric fat in insulin-resistant rats. Life Sci 1999; 65: 237-44.
12. Lira FS, Rosa JC, Yamashita AS, et al. Endurance training induces depot-specific changes in IL-10/TNF-alpha ratio in rat adipose tissue. Cytokine 2009; 45: 80-5.
13. Kaur K, Sharma AK, Dhingra S, Singal PK. Interplay of TNFalpha and IL-10 in regulating oxidative stress in isolated adult cardiac myocytes. J Mol Cell Cardiol 2006; 41: 1023-30.
14. Berzosa C, Cebrian I, Fuentes-Broto L, et al. Acute exercise increases plasma total antioxidant status and antioxidant enzyme activities in untrained men. J Biomed Biotechnol 2011; 2011: 540-8.
15. Barreiro E, De la Puente B, Busquets S, et al. Both oxidative and nitrosative stress are associated with muscle wasting in tumour-bearing rats. FEBS Lett 2005; 579: 1646-52.
16. Nilsson J, Jovinge S, Niemann A, Reneland R, Lithell H. Relation between plasma tumour necrosis factor alpha and insulin sensitivity in elderly men with non-insulin-dependent diabetes mellitus. Arterioscler Thromb Vasc Biol 1998; 18 :1199-202.
17. McGee SL, Mustard KJ, Hardie DG, Baar K. Normal hypertrophy accompanied by phosphoryation and activation of AMP-activated protein kinase alpha1 following overload in LKB1 knockout mice. J Physiol 2008; 586: 1731-41.
18. Stitt TN, Drujan D, Clarke BA, et al. The IGF-1/PI3K/ Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors. Molecular Cell 2004; 14: 395-403.
19. Poehlman ET, Dvorak RV, DeNino WF, Brochu M, Ades PA. Effects of resistance training and endurance training on insulin sensitivity in non-obese, young women: a controlled randomized trial. J Clin Endocrinol Metab 2000; 85: 2463-8.
20. Wu H, Naya FJ, McKinsey TA, et al. MEF2 responds to multiple calcium-regulated signals in the control of skeletal muscle fiber type. EMBO 2000; 19: 1963-73.
21. McGee SL, Hargreaves M. Exercise and myocyte enhancer factor 2 regulation in human skeletal muscle. Diabetes 2004; 53: 1208-14.
22. Wilkinson SB, Phillips SM, Atherton PJ, et al. Differential effects of resistance and endurance exercise in the fed state on signalling molecule phosphorylation and protein synthesis in human muscle. J Physiol 2008; 586: 3701-17.
23. Edinger AL, Thompson CB. Akt maintains cell size and survival by increasing mTOR-dependent nutrient uptake. Mol Biol Cell 2002; 13: 2276-88.
24. Bamman MM, Shipp JR, Jiang J, et al. Mechanical load increases muscle IGF-I and androgen receptor mRNA concentrations in humans. Am J Physiol Endocrinol Metab 2001; 280: E383-90.
25. Tsakiridis T, Tsiani E, Lekas P, et al. Insulin, insulin-like growth factor-I, and platelet-derived growth factor activate extracellular signal regulated kinase by distinct pathways in muscle cells. Biochem Biophys Res Commun 2001; 288:205–11.
26. Parkington JD, LeBrasseur NK, Siebert AP, Fielding RA. Contraction-mediated mTOR, p70S6k, and ERK1/2 phosphorylation in aged skeletal muscle. J Appl Physiol 2004; 97: 243-8.
27. National Cancer Institute. Radiation Therapy and You. National Institute of Health 2007; 21-50.
28. Smets EM, Garssen B, Schuster-Uitterhoeve AL, de Haes JC. Fatigue in cancer patients. Br J Cancer 1993; 68: 220–224.
29. Vadhan-Raj S. Management of chemotherapy-induced thrombocytopenia: current status of thrombopoietic agents. Seminars in Hematology 2009; 4 6(1 Suppl 2): S26-32.
30. American College of Sports Medicine. ACSM's exercise management for persons with chronic diseases and disabilities (3rd Ed). Human Kinetics, 2009; Chapter 27.