Bibliografia

1. Eckel RH, Krauss RM. American Heart Association call to action: Obesity as a major risk factor for coronary heart disease. Circulation 1998; 97: 2099-100.

2. Freedman DS, Srinivasan SR, Valdez RA et al. Secular increases in relative weight and adiposity among children over two decades: the Bogalusa Heart Study. Pediatrics 1997; 99: 420-6.

3. Troiano RP, Flegal KM. Overweight children and adolescents: description, epidemiology and demographics. Pediatrics 1998; 101: 497-504.

4. Reilly JJ, Dorosty AR, Emmett PM. Prevalence of overweight and obesity in British children: cohort study. BMJ 1999; 319: 1039-41.

5. Deckelbaum RJ, Williams CL. Childhood obesity: the health issue. Obes Rev 2001; 9(Suppl 4): 239S-243S.

6. Schonfeld-Warden N, Warden CH. Pediatric obesity. An overview of etiology and treatment. Ped Endocrin 1997; 44: 339-60.

7. Must A, Jacques PF, Dallal GE et al. Long-term morbidity and mortality of overweight adolescents: A follow up of the Harvard Growth Study of 1922-1935. N Engl J Med 1992; 327: 1350-5.

8. Mossberg HO. 40-year follow-up of overweight children. Lancet 1989; 2: 491-3.

9. Rosenbaum M, Leibel RL, Hirsch J. Obesity. N Engl J Med 1997; 337: 396-407.

10. Promoting better health for young people through physical activity and sports. A report to the President from the Secretary of Health and Human Services and the Secretary of Education. US Department of Health and Human Services and Department of Education; 2000.

11. Moon L, Meyer P, Grau J. Australia's young people: their health and wellbeing 1999. Australian Institute of Health and Welfare (AIHW) Cat. No. PHE 19 1999; Canberra: AIHW.

12. Powell KE, Dysinger W. Childhood participation in organised school sports and physical education as precursors of adult physical activity. Am J Prevent Med 1987; 3: 276-81.

13. Riddoch C. Relationships between physical activity and physical health in young people. In: Biddle S, Sallis J, Cavill N, eds. Young and Active? Young People and Health-Enhancing Physical Activity. Evidence and Implications. London: Health Education Authority; 1998.

14. Nutbeam D, Wise M, Bauman A et al. Goals and targets for Australia's health in the year 2000 and beyond. Canberra: Commonwealth Dept. Health, Housing and Community Services; 1993.

15. Harrison DG. Cellular and molecular mechanisms of endothelial cell dysfunction. J Clin Invest 1997; 100: 2153-7.

16. Schachinger V, Britten MB, Zeiher AM. Prognostic impact of coronary vasodilator dysfunction on adverse long-term outcome of coronary heart disease. Circulation 2000; 101(16): 1899-906.

17. Al Suwaidi J, Hamasaki S, Higano ST et al. Long-term follow-up of patients with mild coronary artery disease and endothelial dysfunction. Circulation 2000; 101: 948-54.

18. Halcox JP, Schenke WH, Zalos G et al. Prognostic value of coronary vascular endothelial function. Circulation 2002; 106: 653-8.

19. Heitzer T, Schlinzig T, Krohn K et al. Endothelial dysfunction, oxidative stress, and risk of cardiovascular events in patients with coronary artery disease. Circulation 2001; 104: 2673-8.

20. Perticone F, Ceravolo R, Puji A et al. Prognostic significance of endothelial dysfunction in hypertensive patients. Circulation 2001; 104: 191-6.

21. Gocke N, Keaney JF, Hunter LM et al. Risk stratification for postoperative cardiovascular events via noninvasive assessment of endothelial function: a prospective study. Circulation 2002; 105: 1567-72.

22. Neunteufl T, Heher S, Katzenschlager R et al. Late prognostic value of flow-mediated dilation in the brachial artery of patients with chest pain. Am J Cardiol 2000; 86: 207-10.

23. O'Driscoll JG, Green DJ, Maiorana A et al. Improvement in endothelial function by ACE inhibition in non-insulin-dependent diabetes mellitus. J Am Coll Cardiol 1999; 33: 1506-11.

24. O'Driscoll G, Green D, Taylor R. Simvastatin, an HMG-Coenzyme A reductase inhibitor, improves endothelial function within 1 month. Circulation 1997; 95: 1126-31.

25. Hambrecht R, Wolf A, Geilen S et al. Effect of exercise on coronary endothelial function in patients with coronary artery disease. N Engl J Med 2000; 342: 454-60.

26. Belardinelli R, Georgiou D, Cianci G et al. Randomised, controlled trial of long-term moderate exercise training in chronic heart failure. Effects on functional capacity, quality of life, and clinical outcome. Circulation 1999; 99: 1173-82.

27. Vita JA, Keaney JF. Endothelial function: a barometer for cardiovascular risk? (Editorial). Circulation 2002; 106: 640-2.

28. Modena MG, Bonetti L, Coppi F et al. Prognostic role of reversible endothelial dysfunction in hypertensive postmenopausal women. J Am Coll Cardiol 2002; 40: 505-10.

29. Sorensen KE, Celermajer DS, Spiegelhalter DJ et al. Non-invasive measurement of human endothelium dependent arterial responses: accuracy and reliability. Br Heart J 1995; 74: 247-53.

30. Celermajer DS, Sorensen KE, Georgakopoulos D et al. Cigarette smoking is associated with dose-related and potentially reversible impairment of endothelium-dependent dilation in healthy young adults. Circulation 1993; 88: 2149-55.

31. Celermajer DS, Sorensen K, Ryalls M et al. Impaired endothelial function occurs in the systemic arteries of children with homozygous homocystinuria but not their heterozygous parents. J Am Coll Cardiol 1993; 22: 854-8.

32. Sorensen KE, Celermajer DS, Georgakopolous D et al. Impairment of endothelium-dependent dilation is an early event in children with familial hypercholesterolaemia and is related to lipoprotein(a) level. J Clin Invest 1994; 93: 50-5.

33. Maiorana A, O'Driscoll G, Cheetham C et al. The effect of combined aerobic and resistance exercise training on vascular function in type 2 diabetes. J Am Coll Cardiol 2001; 38: 860-6.

34. Maiorana A, Cheetham C, Collis J et al. Effect of circuit weight training on functional capacity and vascular function in non-insulin dependent diabetes. Circulation 1999; 100: I-796.

35. Tounian P, Aggoun Y, Dubern B et al. Presence of increased stiffness of the common carotid artery and endothelial dysfunction in severely obese children: a prospective study. Lancet 2001; 358: 1400-4.

36. Watts K, Beye P, Siafarikas A et al. Exercise training normalises vascular dysfunction and improves central adiposity in obese adolescents. J Am Coll Cardiol 2004; 43: 1823-7.

37. Watts K, Beye P, Siafarikas A et al. Effects of exercise training on vascular function in obese children. J Pediatrics 2004; 144: 620-5.

38. Woo KS, Chook P, Yu CW et al. Effects of diet and exercise on obesity-related vascular dysfunction in children. Circulation 2004; 109: 1981-6.

39. Pohl U, Holtz J, Busse R et al. Crucial role of endothelium in the vasodilator response to increased flow in vivo. Hypertension 1986; 8: 37-44.

40. Hambrecht R, Adams V, Erbs S et al. Regular physical activity improves endothelial function in patients with coronary artery disease by increasing phosphorylation of endothelial nitric oxide synthase. Circulation 2003; 107: 3152-8.

41. Green D, Maiorana A, O'Driscoll G, Taylor RR. Effect of exercise training on endothelium-derived nitric oxide function in humans. J Physiol 2004; In Press.

42. Farrell SW, Braun L, Barlow CE et al. The relation of body mass index, cardiorespiratory fitness, and all-cause mortality in women. Obes Res 2002; 10: 417-23.

43. Barlow CE, Kohl HW, Gibbons LW et al. Physical fitness, mortality and obesity. Int J Obes 1995; 19(Suppl 4): S41-44.

44. Blair SN, Cheng YJ, Holder JS. Is physical activity or physical fitness more important in defining health benefits. Med Sci Sports Exerc 2001; 33(Suppl 6): S379-S399.